Dr. Sun’s research interests focus on studying the roles of ion transporter proteins, such as Na-K-Cl cotransporters, Na/Ca exchangers, and Na/H exchangers, in ionic dysregulation and neurodegeneration in experimental models of ischemic stroke, traumatic brain injury, and glioblastoma. The ion transporter proteins are pathologically stimulated under these disease conditions. The dysregulated ion transport function further interrupts the cellular and metabolic equilibrium. Dr. Sun’s lab is investigating the underlying mechanisms and modulating ion transport protein function as novel therapeutic strategy for these brain disorders.