Paul Palevsky, MD

Veterans Health Foundation

Paul Palevsky, MD

Dr. Palevsky completed his undergraduate and medical education at Northwestern University followed by internship and residency training in internal medicine and fellowship training in nephrology at the Hospitals of the University of Pennsylvania. Dr. Palevsky joined the faculty at the University of Pittsburgh and the VA Pittsburgh Healthcare System in 1989 and is currently a Professor of Medicine and Clinical and Translational Science in the Renal-Electrolyte Division at the University of Pittsburgh School of Medicine, a member of the Center for Critical Care Nephrology in the Department of Critical Care Medicine at the University of Pittsburgh and Chief of the Renal Section at the VA Pittsburgh Healthcare System.

Dr. Palevsky’ s research has primarily focused on acute kidney injury and critical care nephrology. Among other clinical trials, he was the study chair of the VA/NIH Acute Renal Failure Trial Network (ATN) Study (VA Cooperative Study #530) evaluating the intensity of renal replacement therapy in critically ill patients with acute kidney injury and currently serves as co-chair of the PRESERVE trial (VA Cooperative Study #578), evaluating the comparative effectiveness of saline and bicarbonate and the efficacy of N-acetylcysteine in preventing kidney damage following angiography. Dr. Palevsky also served on the planning and executive committees of the VA NEPHRON-D study (VA Cooperative Study #565) which compared the use of combination therapy with an angiotensin converting enzyme inhibitor and an angiotensin receptor blocker with monotherapy with an angiotensin receptor blocker on the progression of kidney disease in patients with type 2 diabetes mellitus. Dr. Palevsky also serves on the steering committee of the EUPHRATES trial, evaluating the use of Polymyxin B hemoperfusion in adults with endotoxemia and septic shock.

Dr. Palevsky has published more than 200 articles and book chapters and has lectured extensively in the United States and internationally. Dr. Palevsky currently serves as deputy editor of the Clinical Journal of the American Society of Nephrology and as the section editor for Renal Failure for UpToDate.

Investigator Research Interests


  • Chief, Renal Section, VA Pittsburgh Healthcare System
  • Professor of Medicine (Renal) and Clinical & Translational Science, University of Pittsburgh

What are the 3 most important questions that define your research program?

  1. What strategies are most effective to prevent acute kidney injury?
  2. What are the best strategies for management of renal replacement therapy in patients with acute kidney injury
  3. Does acute kidney injury contribute to the development and/or progression of chronic kidney disease?

What are five key words that best describe your areas of interest?

  1. Acute kidney injury
  2. Renal replacement therapy
  3. Hemodialysis
  4. Hemofiltration
  5. Chronic kidney disease